Police said Symonds was driving on Hervey Range Road, about 50 km from Townsville, around 11 p.m. yesterday when his SUV skidded off the road and flipped.
Emergency services attempted to revive the 46-year-old man, but he died at the scene.
Patrol Inspector Gavin Oates said the cause of the crash is still unknown.
“That is still being investigated at this stage. Officers from the Accident Forensic Unit have attended the scene and are conducting the investigation and will prepare a report for the coroner,” Oates said.
“The accident was heard by people nearby, they were the first people on the scene and they alerted the emergency services.
“I believe the driver of the vehicle had been ejected from the vehicle during the crash.”
Oates said police officers on the scene didn’t immediately realize it was Symonds.
“Police were dealing with the accident side at the time and worked to establish the person’s identity later on,” he said.
Tributes have poured in from the cricket community and from Australian leaders for Symonds, a charismatic all-rounder and one of the best fielders the game has seen.
“Australian cricket is shocked and saddened by the news of the passing of Andrew Symonds,” Cricket Australia said in a statement.
Cricket Australia chief executive Nick Hockley said Symonds was a “much loved and admired cricketer”.
“He was a prodigious talent from a young age in Queensland with his clean striking ability, cunning bowling and brilliant fielding,” he said.
“He will be sadly missed by the Australian cricket community and, in particular, by his closest friends at the Queensland Bulls, where he was a popular and much admired teammate and friend.
“Our thoughts are with his family and friends at this devastatingly sad time.”
Queensland Cricket chairman Chris Simpson said the loss of Symonds will be mourned by the cricket community and the world.
“On behalf of Queensland Cricket, we extend our deepest condolences to his family and will do everything we can to help them,” he said.
“It is a devastating loss for those closest to him and his wide circle of friends that stretches to every corner of the cricketing world.”
NSW Premier Dominic Perrottet said it was “shocking and sad news”.
“Such an entertaining player and such a great cricket character,” said Perrottet.
Queensland Premier Annastacia Palaszczuk also paid tribute to the cricketer.
“Andrew Symonds was a dynamic, entertaining and skilful standout player who made an unforgettable contribution to Queensland and Australian cricket,” he said.
Symonds played 26 tests for Australia between 2004 and 2008, and 198 one-day internationals, and was a member of two World Cup-winning teams in 2003 and 2007.
His death comes just months after the loss of teammate Shane Warne at just 52 years old and former goalkeeper Rod Marsh.
His last post was about Warne, saying that he “hoped it was all a bad dream.”